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Loss-of-function of p53 isoform Δ113p53 accelerates brain aging in zebrafish

Reactive oxygen species (ROS) stress has been demonstrated as potentially critical for induction and maintenance of cellular senescence, and been considered as a contributing factor in aging and in various neurological disorders including Alzheimer’s disease (AD) and amyotrophic lateral sclerosis (A...

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Detalles Bibliográficos
Autores principales: Zhao, Ting, Ye, Shengfan, Tang, Zimu, Guo, Liwei, Ma, Zhipeng, Zhang, Yuxi, Yang, Chun, Peng, Jinrong, Chen, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7862496/
https://www.ncbi.nlm.nih.gov/pubmed/33542214
http://dx.doi.org/10.1038/s41419-021-03438-9