Levomepromazine and clozapine induce the main human cytochrome P450 drug metabolizing enzyme CYP3A4

BACKGROUND: Cytochrome P450 (CYP) enzymes are involved in the metabolism of many important endogenous substrates (steroids, melatonin), drugs and toxic xenobiotics. Their induction accelerates drug metabolism and elimination. The present study aimed at examining the inducing abilities of two antipsy...

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Detalles Bibliográficos
Autores principales: Danek, Przemysław J., Basińska-Ziobroń, Agnieszka, Wójcikowski, Jacek, Daniel, Władysława A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7862537/
https://www.ncbi.nlm.nih.gov/pubmed/32888176
http://dx.doi.org/10.1007/s43440-020-00157-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7862537/
https://www.ncbi.nlm.nih.gov/pubmed/32888176
http://dx.doi.org/10.1007/s43440-020-00157-4

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