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Levomepromazine and clozapine induce the main human cytochrome P450 drug metabolizing enzyme CYP3A4
BACKGROUND: Cytochrome P450 (CYP) enzymes are involved in the metabolism of many important endogenous substrates (steroids, melatonin), drugs and toxic xenobiotics. Their induction accelerates drug metabolism and elimination. The present study aimed at examining the inducing abilities of two antipsy...
Autores principales: | Danek, Przemysław J., Basińska-Ziobroń, Agnieszka, Wójcikowski, Jacek, Daniel, Władysława A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7862537/ https://www.ncbi.nlm.nih.gov/pubmed/32888176 http://dx.doi.org/10.1007/s43440-020-00157-4 |
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