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In utero Therapy for the Treatment of Sickle Cell Disease: Taking Advantage of the Fetal Immune System

Sickle Cell Disease (SCD) is an autosomal recessive disorder resulting from a β-globin gene missense mutation and is among the most prevalent severe monogenic disorders worldwide. Haematopoietic stem cell transplantation remains the only curative option for the disease, as most management options fo...

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Detalles Bibliográficos
Autores principales: Cortabarria, Alba Saenz de Villaverde, Makhoul, Laura, Strouboulis, John, Lombardi, Giovanna, Oteng-Ntim, Eugene, Shangaris, Panicos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7862553/
https://www.ncbi.nlm.nih.gov/pubmed/33553164
http://dx.doi.org/10.3389/fcell.2020.624477