Chronic Hyperglycemia Drives Functional Impairment of Lymphocytes in Diabetic INS(C94Y) Transgenic Pigs

People with diabetes mellitus have an increased risk for infections, however, there is still a critical gap in precise knowledge about altered immune mechanisms in this disease. Since diabetic INS(C94Y) transgenic pigs exhibit elevated blood glucose and a stable diabetic phenotype soon after birth,...

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Detalles Bibliográficos
Autores principales: Giese, Isabella-Maria, Schilloks, Marie-Christin, Degroote, Roxane L., Weigand, Maria, Renner, Simone, Wolf, Eckhard, Hauck, Stefanie M., Deeg, Cornelia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7862560/
https://www.ncbi.nlm.nih.gov/pubmed/33552065
http://dx.doi.org/10.3389/fimmu.2020.607473

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7862560/
https://www.ncbi.nlm.nih.gov/pubmed/33552065
http://dx.doi.org/10.3389/fimmu.2020.607473

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