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Chronic Hyperglycemia Drives Functional Impairment of Lymphocytes in Diabetic INS(C94Y) Transgenic Pigs
People with diabetes mellitus have an increased risk for infections, however, there is still a critical gap in precise knowledge about altered immune mechanisms in this disease. Since diabetic INS(C94Y) transgenic pigs exhibit elevated blood glucose and a stable diabetic phenotype soon after birth,...
Autores principales: | Giese, Isabella-Maria, Schilloks, Marie-Christin, Degroote, Roxane L., Weigand, Maria, Renner, Simone, Wolf, Eckhard, Hauck, Stefanie M., Deeg, Cornelia A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7862560/ https://www.ncbi.nlm.nih.gov/pubmed/33552065 http://dx.doi.org/10.3389/fimmu.2020.607473 |
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