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SHP2 Nuclear/Cytoplasmic Trafficking in Granulosa Cells Is Essential for Oocyte Meiotic Resumption and Maturation

Src-homology-2-containing phosphotyrosine phosphatase (SHP2), a classic cytoplasmic protein and a major regulator of receptor tyrosine kinases and G protein-coupled receptors, plays a significant role in preimplantation embryo development. In this study, we deciphered the role of SHP2 in the somatic...

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Detalles Bibliográficos
Autores principales: Idrees, Muhammad, Kumar, Vikas, Joo, Myeong-Don, Ali, Niaz, Lee, Keun-Woo, Kong, Il-Keun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7862566/
https://www.ncbi.nlm.nih.gov/pubmed/33553147
http://dx.doi.org/10.3389/fcell.2020.611503