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Gametes deficient for Pot1 telomere binding proteins alter levels of telomeric foci for multiple generations

Deficiency for telomerase results in transgenerational shortening of telomeres. However, telomeres have no known role in transgenerational epigenetic inheritance. C. elegans Protection Of Telomeres 1 (Pot1) proteins form foci at the telomeres of germ cells that disappear at fertilization and gradual...

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Detalles Bibliográficos
Autores principales: Lister-Shimauchi, Evan H., Dinh, Michael, Maddox, Paul, Ahmed, Shawn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7862594/
https://www.ncbi.nlm.nih.gov/pubmed/33542458
http://dx.doi.org/10.1038/s42003-020-01624-7