Synergistic inhibition of histone modifiers produces therapeutic effects in adult Shank3-deficient mice

Autism spectrum disorder (ASD) is a lifelong developmental disorder characterized by social deficits and other behavioral abnormalities. Dysregulation of epigenetic processes, such as histone modifications and chromatin remodeling, have been implicated in ASD pathology, and provides a promising ther...

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Detalles Bibliográficos
Autores principales: Zhang, Freddy, Rein, Benjamin, Zhong, Ping, Shwani, Treefa, Conrow-Graham, Megan, Wang, Zi-Jun, Yan, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7862604/
https://www.ncbi.nlm.nih.gov/pubmed/33542189
http://dx.doi.org/10.1038/s41398-021-01233-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7862604/
https://www.ncbi.nlm.nih.gov/pubmed/33542189
http://dx.doi.org/10.1038/s41398-021-01233-w

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