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The mitotic checkpoint is a targetable vulnerability of carboplatin-resistant triple negative breast cancers
Triple-negative breast cancer (TNBC) is the most aggressive breast cancer subtype, lacking effective therapy. Many TNBCs show remarkable response to carboplatin-based chemotherapy, but often develop resistance over time. With increasing use of carboplatin in the clinic, there is a pressing need to i...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7862668/ https://www.ncbi.nlm.nih.gov/pubmed/33542435 http://dx.doi.org/10.1038/s41598-021-82780-6 |