The mitotic checkpoint is a targetable vulnerability of carboplatin-resistant triple negative breast cancers

Triple-negative breast cancer (TNBC) is the most aggressive breast cancer subtype, lacking effective therapy. Many TNBCs show remarkable response to carboplatin-based chemotherapy, but often develop resistance over time. With increasing use of carboplatin in the clinic, there is a pressing need to i...

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Detalles Bibliográficos
Autores principales: Moens, Stijn, Zhao, Peihua, Baietti, Maria Francesca, Marinelli, Oliviero, Van Haver, Delphi, Impens, Francis, Floris, Giuseppe, Marangoni, Elisabetta, Neven, Patrick, Annibali, Daniela, Sablina, Anna A., Amant, Frédéric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7862668/
https://www.ncbi.nlm.nih.gov/pubmed/33542435
http://dx.doi.org/10.1038/s41598-021-82780-6

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