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The novel ZEB1-upregulated protein PRTG induced by Helicobacter pylori infection promotes gastric carcinogenesis through the cGMP/PKG signaling pathway

Helicobacter pylori (H. pylori) is listed as a class I carcinogen in human gastric cancer; however, the underlying mechanisms are poorly understood. In this study, we identified Protogenin (PRTG) was upregulated in both gastric cancer tissues and H. pylori-infected tissues by analyzing dysregulated...

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Detalles Bibliográficos
Autores principales: Xiang, Tian, Yuan, Chunhui, Guo, Xia, Wang, Honghao, Cai, Qinzhen, Xiang, Yun, Luo, Wei, Liu, Gao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7862680/
https://www.ncbi.nlm.nih.gov/pubmed/33542225
http://dx.doi.org/10.1038/s41419-021-03440-1