VEGFR2 Trafficking by KIF13B Is a Novel Therapeutic Target for Wet Age-Related Macular Degeneration

PURPOSE: Vascular endothelial growth factor (VEGF) and its receptor VEGFR2 are promising therapeutic targets for wet age-related macular degeneration (AMD). As a topically applicable option, we developed the peptide KAI to selectively interfere with VEGFR2 trafficking to the cell surface where it re...

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Detalles Bibliográficos
Autores principales: Waters, Stephen B., Zhou, Christopher, Nguyen, Tara, Zelkha, Ruth, Lee, Hyun, Kazlauskas, Andrius, Rosenblatt, Mark I., Malik, Asrar B., Yamada, Kaori H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2021
Materias:
Physiology and Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7862734/
https://www.ncbi.nlm.nih.gov/pubmed/33533881
http://dx.doi.org/10.1167/iovs.62.2.5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7862734/
https://www.ncbi.nlm.nih.gov/pubmed/33533881
http://dx.doi.org/10.1167/iovs.62.2.5

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