Neonatal AAV gene therapy rescues hearing in a mouse model of SYNE4 deafness

Genetic variants account for approximately half the cases of congenital and early‐onset deafness. Methods and technologies for viral delivery of genes into the inner ear have evolved over the past decade to render gene therapy a viable and attractive approach for treatment. Variants in SYNE4, encodi...

Descripción completa

Detalles Bibliográficos
Autores principales: Taiber, Shahar, Cohen, Roie, Yizhar‐Barnea, Ofer, Sprinzak, David, Holt, Jeffrey R, Avraham, Karen B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7863404/
https://www.ncbi.nlm.nih.gov/pubmed/33350593
http://dx.doi.org/10.15252/emmm.202013259

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7863404/
https://www.ncbi.nlm.nih.gov/pubmed/33350593
http://dx.doi.org/10.15252/emmm.202013259

Ejemplares similares