Local anesthetics impair the growth and self-renewal of glioblastoma stem cells by inhibiting ZDHHC15-mediated GP130 palmitoylation

BACKGROUND: A large number of preclinical studies have shown that local anesthetics have a direct inhibitory effect on tumor biological activities, including cell survival, proliferation, migration, and invasion. There are few studies on the role of local anesthetics in cancer stem cells. This study...

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Detalles Bibliográficos
Autores principales: Fan, Xiaoqing, Yang, Haoran, Zhao, Chenggang, Hu, Lizhu, Wang, Delong, Wang, Ruiting, Fang, Zhiyou, Chen, Xueran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7863430/
https://www.ncbi.nlm.nih.gov/pubmed/33541421
http://dx.doi.org/10.1186/s13287-021-02175-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7863430/
https://www.ncbi.nlm.nih.gov/pubmed/33541421
http://dx.doi.org/10.1186/s13287-021-02175-2

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