Cargando…

Overexpression of SP1 restores autophagy to alleviate acute renal injury induced by ischemia-reperfusion through the miR-205/PTEN/Akt pathway

BACKGROUND: Acute kidney injury (AKI) is a major kidney disease with poor clinical outcome. SP1, a well-known transcription factor, plays a critical role in AKI and subsequent kidney repair through the regulation of various cell biologic processes. However, the underlying mechanism of SP1 in these p...

Descripción completa

Detalles Bibliográficos
Autores principales: Huang, Chong, Chen, Yan, Lai, Bin, Chen, Yan-Xia, Xu, Cheng-Yun, Liu, Yuan-Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7863508/
https://www.ncbi.nlm.nih.gov/pubmed/33546692
http://dx.doi.org/10.1186/s12950-021-00270-y