Overexpression of SP1 restores autophagy to alleviate acute renal injury induced by ischemia-reperfusion through the miR-205/PTEN/Akt pathway

BACKGROUND: Acute kidney injury (AKI) is a major kidney disease with poor clinical outcome. SP1, a well-known transcription factor, plays a critical role in AKI and subsequent kidney repair through the regulation of various cell biologic processes. However, the underlying mechanism of SP1 in these p...

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Detalles Bibliográficos
Autores principales: Huang, Chong, Chen, Yan, Lai, Bin, Chen, Yan-Xia, Xu, Cheng-Yun, Liu, Yuan-Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7863508/
https://www.ncbi.nlm.nih.gov/pubmed/33546692
http://dx.doi.org/10.1186/s12950-021-00270-y

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