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AG490, a JAK2-specific inhibitor, downregulates the expression and activity of organic anion transporter-3
Human organic anion transporter-3 (hOAT3) is richly expressed in the kidney, where it plays critical roles in the secretion of clinically important drugs, including anti-viral therapeutics, anti-cancer drugs, antibiotics, antihypertensives, and anti-inflammatories. In the current study, we examined...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7863619/ https://www.ncbi.nlm.nih.gov/pubmed/29487013 http://dx.doi.org/10.1016/j.jphs.2018.01.006 |