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AG490, a JAK2-specific inhibitor, downregulates the expression and activity of organic anion transporter-3

Human organic anion transporter-3 (hOAT3) is richly expressed in the kidney, where it plays critical roles in the secretion of clinically important drugs, including anti-viral therapeutics, anti-cancer drugs, antibiotics, antihypertensives, and anti-inflammatories. In the current study, we examined...

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Detalles Bibliográficos
Autores principales: Zhang, Jinghui, Liu, Chenchang, You, Guofeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7863619/
https://www.ncbi.nlm.nih.gov/pubmed/29487013
http://dx.doi.org/10.1016/j.jphs.2018.01.006