TGFβ-1 Induced Cross-Linking of the Extracellular Matrix of Primary Human Dermal Fibroblasts

Excessive cross-linking is a major factor in the resistance to the remodelling of the extracellular matrix (ECM) during fibrotic progression. The role of TGFβ signalling in impairing ECM remodelling has been demonstrated in various fibrotic models. We hypothesised that increased ECM cross-linking by...

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Detalles Bibliográficos
Autores principales: Semkova, Mariya E., Hsuan, J. Justin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7863744/
https://www.ncbi.nlm.nih.gov/pubmed/33498156
http://dx.doi.org/10.3390/ijms22030984

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7863744/
https://www.ncbi.nlm.nih.gov/pubmed/33498156
http://dx.doi.org/10.3390/ijms22030984

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