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Epigenetic identification of mitogen-activated protein kinase 10 as a functional tumor suppressor and clinical significance for hepatocellular carcinoma

BACKGROUND: Mitogen-activated protein kinase 10 (Mapk10) is a member of the c-jun N-terminal kinases (jnk) subgroup in the MAPK superfamily, and was proposed as a tumor suppressor inactivated epigenetically. Its role in hepatocellular carcinoma (HCC) has not yet been illustrated. We aimed to investi...

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Detalles Bibliográficos
Autores principales: Tang, Liping, Zhu, Shasha, Peng, Weiyan, Yin, Xuedong, Tan, Cui, Yang, Yaying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7863782/
https://www.ncbi.nlm.nih.gov/pubmed/33604188
http://dx.doi.org/10.7717/peerj.10810