Cargando…

Cholesterol sensing by CD81 is important for hepatitis C virus entry

CD81 plays a central role in a variety of physiological and pathological processes. Recent structural analysis of CD81 indicates that it contains an intramembrane cholesterol-binding pocket and that interaction with cholesterol may regulate a conformational switch in the large extracellular domain o...

Descripción completa

Detalles Bibliográficos
Autores principales: Palor, Machaela, Stejskal, Lenka, Mandal, Piya, Lenman, Annasara, Alberione, María Pía, Kirui, Jared, Moeller, Rebecca, Ebner, Stefan, Meissner, Felix, Gerold, Gisa, Shepherd, Adrian J., Grove, Joe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7863897/
https://www.ncbi.nlm.nih.gov/pubmed/32900848
http://dx.doi.org/10.1074/jbc.RA120.014761