Differential microRNA Expression in USP8-Mutated and Wild-Type Corticotroph Pituitary Tumors Reflect the Difference in Protein Ubiquitination Processes

Background: USP8 mutations are the most common driver changes in corticotroph pituitary tumors. They have direct effect on cells’ proteome through disturbance of ubiquitination process and also influence gene expression. The aim of this study was to compare microRNA profiles in USP8-mutated and wild...

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Detalles Bibliográficos
Autores principales: Bujko, Mateusz, Kober, Paulina, Boresowicz, Joanna, Rusetska, Natalia, Zeber-Lubecka, Natalia, Paziewska, Agnieszka, Pekul, Monika, Zielinski, Grzegorz, Styk, Andrzej, Kunicki, Jacek, Ostrowski, Jerzy, Siedlecki, Janusz A, Maksymowicz, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7863919/
https://www.ncbi.nlm.nih.gov/pubmed/33498176
http://dx.doi.org/10.3390/jcm10030375

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7863919/
https://www.ncbi.nlm.nih.gov/pubmed/33498176
http://dx.doi.org/10.3390/jcm10030375

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