Role of HMOX1 Promoter Genetic Variants in Chemoresistance and Chemotherapy Induced Neutropenia in Children with Acute Lymphoblastic Leukemia

Whilst the survival rates of childhood acute lymphoblastic leukemia (ALL) have increased remarkably over the last decades, the therapy resistance and toxicity are still the major causes of treatment failure. It was shown that overexpression of heme oxygenase-1 (HO-1) promotes proliferation and chemo...

Descripción completa

Detalles Bibliográficos
Autores principales: Bukowska-Strakova, Karolina, Włodek, Joanna, Pitera, Ewelina, Kozakowska, Magdalena, Konturek-Cieśla, Anna, Cieśla, Maciej, Gońka, Monika, Nowak, Witold, Wieczorek, Aleksandra, Pawińska-Wąsikowska, Katarzyna, Józkowicz, Alicja, Siedlar, Maciej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7863945/
https://www.ncbi.nlm.nih.gov/pubmed/33498175
http://dx.doi.org/10.3390/ijms22030988

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7863945/
https://www.ncbi.nlm.nih.gov/pubmed/33498175
http://dx.doi.org/10.3390/ijms22030988

Ejemplares similares