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Serine, glycine and one-carbon metabolism in cancer (Review)

Serine/glycine biosynthesis and one-carbon metabolism are crucial in sustaining cancer cell survival and rapid proliferation, and of high clinical relevance. Excessive activation of serine/glycine biosynthesis drives tumorigenesis and provides a single carbon unit for one-carbon metabolism. One-carb...

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Detalles Bibliográficos
Autores principales: Pan, Sijing, Fan, Ming, Liu, Zhangnan, Li, Xia, Wang, Huijuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7864012/
https://www.ncbi.nlm.nih.gov/pubmed/33491748
http://dx.doi.org/10.3892/ijo.2020.5158