Cargando…

Cutting out the fat: Site-specific deacylation of an ion channel

S-Acylation, a reversible post-translational lipid modification of proteins, controls the properties and function of various proteins, including ion channels. Large conductance Ca(2+)-activated potassium (BK) channels are S-acylated at two sites that impart distinct functional effects. Whereas the e...

Descripción completa

Detalles Bibliográficos
Autores principales: del Rivero Morfin, Pedro J., Ben-Johny, Manu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7864051/
https://www.ncbi.nlm.nih.gov/pubmed/33277403
http://dx.doi.org/10.1074/jbc.H120.016490