Fluorescence assay for simultaneous quantification of CFTR ion-channel function and plasma membrane proximity

The cystic fibrosis transmembrane conductance regulator (CFTR) is a plasma membrane anion channel that plays a key role in controlling transepithelial fluid movement. Excessive activation results in intestinal fluid loss during secretory diarrheas, whereas CFTR mutations underlie cystic fibrosis (CF...

Descripción completa

Detalles Bibliográficos
Autores principales: Prins, Stella, Langron, Emily, Hastings, Cato, Hill, Emily J., Stefan, Andra C., Griffin, Lewis D., Vergani, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Molecular Bases of Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7864054/
https://www.ncbi.nlm.nih.gov/pubmed/32934006
http://dx.doi.org/10.1074/jbc.RA120.014061

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7864054/
https://www.ncbi.nlm.nih.gov/pubmed/32934006
http://dx.doi.org/10.1074/jbc.RA120.014061

Ejemplares similares