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Fluorescence assay for simultaneous quantification of CFTR ion-channel function and plasma membrane proximity

The cystic fibrosis transmembrane conductance regulator (CFTR) is a plasma membrane anion channel that plays a key role in controlling transepithelial fluid movement. Excessive activation results in intestinal fluid loss during secretory diarrheas, whereas CFTR mutations underlie cystic fibrosis (CF...

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Detalles Bibliográficos
Autores principales:	Prins, Stella, Langron, Emily, Hastings, Cato, Hill, Emily J., Stefan, Andra C., Griffin, Lewis D., Vergani, Paola
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2021
Materias:	Molecular Bases of Disease
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7864054/ https://www.ncbi.nlm.nih.gov/pubmed/32934006 http://dx.doi.org/10.1074/jbc.RA120.014061

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