Inhibition of mitochondrial oxidative metabolism attenuates EMCV replication and protects β-cells from virally mediated lysis

Viral infection is one environmental factor that may contribute to the initiation of pancreatic β-cell destruction during the development of autoimmune diabetes. Picornaviruses, such as encephalomyocarditis virus (EMCV), induce a pro-inflammatory response in islets leading to local production of cyt...

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Detalles Bibliográficos
Autores principales: Stafford, Joshua D., Shaheen, Zachary R., Yeo, Chay Teng, Corbett, John A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Metabolism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7864063/
https://www.ncbi.nlm.nih.gov/pubmed/32972972
http://dx.doi.org/10.1074/jbc.RA120.014851

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7864063/
https://www.ncbi.nlm.nih.gov/pubmed/32972972
http://dx.doi.org/10.1074/jbc.RA120.014851

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