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Inhibition of mitochondrial oxidative metabolism attenuates EMCV replication and protects β-cells from virally mediated lysis

Viral infection is one environmental factor that may contribute to the initiation of pancreatic β-cell destruction during the development of autoimmune diabetes. Picornaviruses, such as encephalomyocarditis virus (EMCV), induce a pro-inflammatory response in islets leading to local production of cyt...

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Detalles Bibliográficos
Autores principales:	Stafford, Joshua D., Shaheen, Zachary R., Yeo, Chay Teng, Corbett, John A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2021
Materias:	Metabolism
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7864063/ https://www.ncbi.nlm.nih.gov/pubmed/32972972 http://dx.doi.org/10.1074/jbc.RA120.014851

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