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Human pancreatic cancer cells under nutrient deprivation are vulnerable to redox system inhibition

Large regions in tumor tissues, particularly pancreatic cancer, are hypoxic and nutrient-deprived because of unregulated cell growth and insufficient vascular supply. Certain cancer cells, such as those inside a tumor, can tolerate these severe conditions and survive for prolonged periods. We hypoth...

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Detalles Bibliográficos
Autores principales: Onodera, Takefumi, Momose, Isao, Adachi, Hayamitsu, Yamazaki, Yohko, Sawa, Ryuichi, Ohba, Shun-ichi, Kawada, Manabu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7864064/
https://www.ncbi.nlm.nih.gov/pubmed/32978257
http://dx.doi.org/10.1074/jbc.RA120.013893