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Spatiotemporal analysis of human intestinal development at single-cell resolution

Development of the human intestine is not well understood. Here, we link single-cell RNA sequencing and spatial transcriptomics to characterize intestinal morphogenesis through time. We identify 101 cell states including epithelial and mesenchymal progenitor populations and programs linked to key mo...

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Detalles Bibliográficos
Autores principales: Fawkner-Corbett, David, Antanaviciute, Agne, Parikh, Kaushal, Jagielowicz, Marta, Gerós, Ana Sousa, Gupta, Tarun, Ashley, Neil, Khamis, Doran, Fowler, Darren, Morrissey, Edward, Cunningham, Chris, Johnson, Paul R.V., Koohy, Hashem, Simmons, Alison
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7864098/
https://www.ncbi.nlm.nih.gov/pubmed/33406409
http://dx.doi.org/10.1016/j.cell.2020.12.016