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Targeting DNA Repair and Chromatin Crosstalk in Cancer Therapy

SIMPLE SUMMARY: Targeting aberrant DNA repair in cancers in addition to transcription and replication is an area of interest for cancer researchers. Inhibition of DNA repair selectively in cancer cells leads to cytotoxic or cytostatic effects and overcomes survival advantages imparted by chromosomal...

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Detalles Bibliográficos
Autores principales: Johnson, Danielle P., Chandrasekharan, Mahesh B., Dutreix, Marie, Bhaskara, Srividya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7864178/
https://www.ncbi.nlm.nih.gov/pubmed/33498525
http://dx.doi.org/10.3390/cancers13030381