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Development of a humanized mouse model to analyze antibodies specific for human leukocyte antigen (HLA)

In organ transplantation, human leukocyte antigen (HLA)-mismatch grafts not only induce the activation of cellular mediated immune response but also the development of chronic antibody-mediated rejection due to the donor-specific anti-HLA antibody (DSA) produced by B cells and plasma cells interacti...

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Detalles Bibliográficos
Autores principales: Yanagawa, Senichiro, Tahara, Hiroyuki, Shirouzu, Takayuki, Kawai, Shintaro, Tanaka, Yuka, Ide, Kentaro, Akimoto, Shuji, Ohdan, Hideki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7864411/
https://www.ncbi.nlm.nih.gov/pubmed/33544740
http://dx.doi.org/10.1371/journal.pone.0236614