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Development of a humanized mouse model to analyze antibodies specific for human leukocyte antigen (HLA)
In organ transplantation, human leukocyte antigen (HLA)-mismatch grafts not only induce the activation of cellular mediated immune response but also the development of chronic antibody-mediated rejection due to the donor-specific anti-HLA antibody (DSA) produced by B cells and plasma cells interacti...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7864411/ https://www.ncbi.nlm.nih.gov/pubmed/33544740 http://dx.doi.org/10.1371/journal.pone.0236614 |