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Transcriptional and immunological analysis of the putative outer membrane protein and vaccine candidate TprL of Treponema pallidum

BACKGROUND: An effective syphilis vaccine should elicit antibodies to Treponema pallidum subsp. pallidum (T. p. pallidum) surface antigens to induce pathogen clearance through opsonophagocytosis. Although the combination of bioinformatics, structural, and functional analyses of T. p. pallidum genes...

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Detalles Bibliográficos
Autores principales: Haynes, Austin M., Fernandez, Mark, Romeis, Emily, Mitjà, Oriol, Konda, Kelika A., Vargas, Silver K., Eguiluz, Maria, Caceres, Carlos F., Klausner, Jeffrey D., Giacani, Lorenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7864442/
https://www.ncbi.nlm.nih.gov/pubmed/33497377
http://dx.doi.org/10.1371/journal.pntd.0008812