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Transcriptional and immunological analysis of the putative outer membrane protein and vaccine candidate TprL of Treponema pallidum
BACKGROUND: An effective syphilis vaccine should elicit antibodies to Treponema pallidum subsp. pallidum (T. p. pallidum) surface antigens to induce pathogen clearance through opsonophagocytosis. Although the combination of bioinformatics, structural, and functional analyses of T. p. pallidum genes...
Autores principales: | Haynes, Austin M., Fernandez, Mark, Romeis, Emily, Mitjà, Oriol, Konda, Kelika A., Vargas, Silver K., Eguiluz, Maria, Caceres, Carlos F., Klausner, Jeffrey D., Giacani, Lorenzo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7864442/ https://www.ncbi.nlm.nih.gov/pubmed/33497377 http://dx.doi.org/10.1371/journal.pntd.0008812 |
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