Dietary iso-α-acids prevent acetaldehyde-induced liver injury through Nrf2-mediated gene expression

Acetaldehyde is the major toxic metabolite of alcohol (ethanol) and enhances fibrosis of the liver through hepatic stellate cells. Additionally, alcohol administration causes the accumulation of reactive oxygen species (ROS), which induce hepatocyte injury-mediated lipid peroxidation. Iso-α-acids, c...

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Detalles Bibliográficos
Autores principales: Takase, Takahito, Toyoda, Tsudoi, Kobayashi, Naoyuki, Inoue, Takashi, Ishijima, Tomoko, Abe, Keiko, Kinoshita, Hiroshi, Tsuchiya, Youichi, Okada, Shinji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7864453/
https://www.ncbi.nlm.nih.gov/pubmed/33544749
http://dx.doi.org/10.1371/journal.pone.0246327

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7864453/
https://www.ncbi.nlm.nih.gov/pubmed/33544749
http://dx.doi.org/10.1371/journal.pone.0246327

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