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pH-Responsive Redox Nanoparticles Protect SH-SY5Y Cells at Lowered pH in a Cellular Model of Parkinson’s Disease

The damage to SH-SY5Y cells by 6-hydroxydopamine (6-OHDA) is an established cellular model of Parkinson’s disease (PD). Redox nanoparticles are a promising tool for therapy, including neurodegenerative diseases. As pH of the brain tissue at sites affected by PD is lowered down to 6.5, we studied the...

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Detalles Bibliográficos
Autores principales: Pichla, Monika, Bartosz, Grzegorz, Stefaniuk, Ireneusz, Sadowska-Bartosz, Izabela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7864521/
https://www.ncbi.nlm.nih.gov/pubmed/33494255
http://dx.doi.org/10.3390/molecules26030543