A lymph node–targeted Amphiphile vaccine induces potent cellular and humoral immunity to SARS-CoV-2

The profound consequences of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) mandate urgent development of effective vaccines. Here, we evaluated an Amphiphile (AMP) vaccine adjuvant, AMP-CpG, composed of diacyl lipid–modified CpG, admixed with the SARS-CoV-2 Spike-2 receptor binding do...

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Detalles Bibliográficos
Autores principales: Steinbuck, Martin P., Seenappa, Lochana M., Jakubowski, Aniela, McNeil, Lisa K., Haqq, Christopher M., DeMuth, Peter C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7864572/
https://www.ncbi.nlm.nih.gov/pubmed/33547083
http://dx.doi.org/10.1126/sciadv.abe5819

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7864572/
https://www.ncbi.nlm.nih.gov/pubmed/33547083
http://dx.doi.org/10.1126/sciadv.abe5819

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