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Thalamic projections to the subthalamic nucleus contribute to movement initiation and rescue of parkinsonian symptoms

The parafascicular nucleus (Pf) of the thalamus provides major projections to the basal ganglia, a set of subcortical nuclei involved in action initiation. Here, we show that Pf projections to the subthalamic nucleus (STN), but not to the striatum, are responsible for movement initiation. Because th...

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Detalles Bibliográficos
Autores principales: Watson, Glenn D. R., Hughes, Ryan N., Petter, Elijah A., Fallon, Isabella P., Kim, Namsoo, Severino, Francesco Paolo Ulloa, Yin, Henry H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7864574/
https://www.ncbi.nlm.nih.gov/pubmed/33547085
http://dx.doi.org/10.1126/sciadv.abe9192