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Stable transplantation of human mitochondrial DNA by high-throughput, pressurized isolated mitochondrial delivery

Generating mammalian cells with specific mitochondrial DNA (mtDNA)–nuclear DNA (nDNA) combinations is desirable but difficult to achieve and would be enabling for studies of mitochondrial-nuclear communication and coordination in controlling cell fates and functions. We developed ‘MitoPunch’, a pres...

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Detalles Bibliográficos
Autores principales: Sercel, Alexander J, Patananan, Alexander N, Man, Tianxing, Wu, Ting-Hsiang, Yu, Amy K, Guyot, Garret W, Rabizadeh, Shahrooz, Niazi, Kayvan R, Chiou, Pei-Yu, Teitell, Michael A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7864630/
https://www.ncbi.nlm.nih.gov/pubmed/33438576
http://dx.doi.org/10.7554/eLife.63102