Cargando…

Stable transplantation of human mitochondrial DNA by high-throughput, pressurized isolated mitochondrial delivery

Generating mammalian cells with specific mitochondrial DNA (mtDNA)–nuclear DNA (nDNA) combinations is desirable but difficult to achieve and would be enabling for studies of mitochondrial-nuclear communication and coordination in controlling cell fates and functions. We developed ‘MitoPunch’, a pres...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sercel, Alexander J, Patananan, Alexander N, Man, Tianxing, Wu, Ting-Hsiang, Yu, Amy K, Guyot, Garret W, Rabizadeh, Shahrooz, Niazi, Kayvan R, Chiou, Pei-Yu, Teitell, Michael A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2021
Materias:	Cell Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7864630/ https://www.ncbi.nlm.nih.gov/pubmed/33438576 http://dx.doi.org/10.7554/eLife.63102

Ejemplares similares

Generating stable isolated mitochondrial recipient clones in mammalian cells using MitoPunch mitochondrial transfer
por: Sercel, Alexander J., et al.
Publicado: (2021)

Stable retention of chloramphenicol-resistant mtDNA to rescue metabolically impaired cells
por: Dawson, Emma R., et al.
Publicado: (2020)

Pressure-Driven Mitochondrial Transfer Pipeline Generates Mammalian Cells of Desired Genetic Combinations and Fates
por: Patananan, Alexander N., et al.
Publicado: (2020)

Transcriptional, Electrophysiological, and Metabolic Characterizations of hESC-Derived First and Second Heart Fields Demonstrate a Potential Role of TBX5 in Cardiomyocyte Maturation
por: Pezhouman, Arash, et al.
Publicado: (2021)

Identification of an immune gene expression signature associated with favorable clinical features in Treg-enriched patient tumor samples
por: Givechian, Kevin B., et al.
Publicado: (2018)

Image patterned molecular delivery into live cells using gold particle coated substrates
por: Wu, Ting-Hsiang, et al.
Publicado: (2010)

Cell viscoelasticity is linked to fluctuations in cell biomass distributions
por: Nguyen, Thang L., et al.
Publicado: (2020)

Photothermal nanoblade for patterned cell membrane cutting
por: Wu, Ting-Hsiang, et al.
Publicado: (2010)

Bmal1 integrates mitochondrial metabolism and macrophage activation
por: Alexander, Ryan K, et al.
Publicado: (2020)

Mitochondrial volume fraction and translation duration impact mitochondrial mRNA localization and protein synthesis
por: Tsuboi, Tatsuhisa, et al.
Publicado: (2020)

Failed mitochondrial import and impaired proteostasis trigger SUMOylation of mitochondrial proteins
por: Paasch, Florian, et al.
Publicado: (2018)

Mitochondrial Rab GAPs govern autophagosome biogenesis during mitophagy
por: Yamano, Koji, et al.
Publicado: (2014)

ER-associated mitochondrial division links the distribution of mitochondria and mitochondrial DNA in yeast
por: Murley, Andrew, et al.
Publicado: (2013)

Mitochondrial CoQ deficiency is a common driver of mitochondrial oxidants and insulin resistance
por: Fazakerley, Daniel J, et al.
Publicado: (2018)

The mitochondrial permeability transition pore activates the mitochondrial unfolded protein response and promotes aging
por: Angeli, Suzanne, et al.
Publicado: (2021)

MFN2 mediates ER-mitochondrial coupling during ER stress through specialized stable contact sites
por: Gottschalk, Benjamin, et al.
Publicado: (2022)

The Mitochondrial Response to DNA Damage
por: Rong, Ziye, et al.
Publicado: (2021)

Mitochondrial flashes regulate ATP homeostasis in the heart
por: Wang, Xianhua, et al.
Publicado: (2017)

Molecular Machinery and Pathophysiology of Mitochondrial Dynamics
por: Chiu, Yi-Han, et al.
Publicado: (2021)

Vault Nanocapsules as Adjuvants Favor Cell-Mediated over Antibody-Mediated Immune Responses following Immunization of Mice
por: Kar, Upendra K., et al.
Publicado: (2012)

Connexin 43 hemichannels regulate mitochondrial ATP generation, mobilization, and mitochondrial homeostasis against oxidative stress
por: Zhang, Jingruo, et al.
Publicado: (2022)

Folding Mitochondrial-Mediated Cytosolic Proteostasis Into the Mitochondrial Unfolded Protein Response
por: Jenkins, Edmund Charles, et al.
Publicado: (2021)

Assigning mitochondrial localization of dual localized proteins using a yeast Bi-Genomic Mitochondrial-Split-GFP
por: Bader, Gaétan, et al.
Publicado: (2020)

High throughput single cell analysis of mitochondrial heteroplasmy in mitochondrial diseases
por: Maeda, Ryotaro, et al.
Publicado: (2020)

Data on chow, liver tissue and mitochondrial fatty acid compositions as well as mitochondrial proteome changes after feeding mice a western diet for 6–24 weeks
por: Einer, Claudia, et al.
Publicado: (2017)

Crystal Structure of Mitochondrial Fission Complex Reveals Scaffolding Function for Mitochondrial Division 1 (Mdv1) Coiled Coil
por: Zhang, Yan, et al.
Publicado: (2012)

Mitochondrial Ca(2 +) Is Related to Mitochondrial Activity and Dynamic Events in Mouse Oocytes
por: Wang, Feng, et al.
Publicado: (2020)

TEAD4 as an Oncogene and a Mitochondrial Modulator
por: Hsu, Sheng-Chieh, et al.
Publicado: (2022)

OPA1 Modulates Mitochondrial Ca(2+) Uptake Through ER-Mitochondria Coupling
por: Cartes-Saavedra, Benjamín, et al.
Publicado: (2022)

Selections that isolate recombinant mitochondrial genomes in animals
por: Ma, Hansong, et al.
Publicado: (2015)

Dataset of mitochondrial genome variants in oncocytic tumors
por: Lyu, Lihua, et al.
Publicado: (2018)

Mitochondrial fusion is required for spermatogonial differentiation and meiosis
por: Varuzhanyan, Grigor, et al.
Publicado: (2019)

APOE expression and secretion are modulated by mitochondrial dysfunction
por: Wynne, Meghan E, et al.
Publicado: (2023)

High‐throughput screening identifies suppressors of mitochondrial fragmentation in OPA1 fibroblasts
por: Cretin, Emma, et al.
Publicado: (2021)

Augmenter of liver regeneration regulates cellular iron homeostasis by modulating mitochondrial transport of ATP-binding cassette B8
por: Chang, Hsiang-Chun, et al.
Publicado: (2021)

The Role of Mitochondrial Dynamics and Mitophagy in Carcinogenesis, Metastasis and Therapy
por: Wang, Yigang, et al.
Publicado: (2020)

Overcoming hypoxia-induced functional suppression of NK cells
por: Solocinski, Kristen, et al.
Publicado: (2020)

Ubiquilin1 promotes antigen-receptor mediated proliferation by eliminating mislocalized mitochondrial proteins
por: Whiteley, Alexandra M, et al.
Publicado: (2017)

The Dimensions of Primary Mitochondrial Disorders
por: Schlieben, Lea D., et al.
Publicado: (2020)

Mitochondrial autophagy in the sleeping brain
por: Mauri, Sofia, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_h9h9avu1ejf0d1ijmve941dbd4