Global, cell non-autonomous gene regulation drives individual lifespan among isogenic C. elegans

Across species, lifespan is highly variable among individuals within a population. Even genetically identical Caenorhabditis elegans reared in homogeneous environments are as variable in lifespan as outbred human populations. We hypothesized that persistent inter-individual differences in expression...

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Detalles Bibliográficos
Autores principales: Kinser, Holly E, Mosley, Matthew C, Plutzer, Isaac B, Pincus, Zachary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Chromosomes and Gene Expression
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7864635/
https://www.ncbi.nlm.nih.gov/pubmed/33522488
http://dx.doi.org/10.7554/eLife.65026

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7864635/
https://www.ncbi.nlm.nih.gov/pubmed/33522488
http://dx.doi.org/10.7554/eLife.65026

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