Sprouty2 limits intestinal tuft and goblet cell numbers through GSK3β-mediated restriction of epithelial IL-33

Dynamic regulation of intestinal cell differentiation is crucial for both homeostasis and the response to injury or inflammation. Sprouty2, an intracellular signaling regulator, controls pathways including PI3K and MAPKs that are implicated in differentiation and are dysregulated in inflammatory bow...

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Detalles Bibliográficos
Autores principales: Schumacher, Michael A., Hsieh, Jonathan J., Liu, Cambrian Y., Appel, Keren L., Waddell, Amanda, Almohazey, Dana, Katada, Kay, Bernard, Jessica K., Bucar, Edie B., Gadeock, Safina, Maselli, Kathryn M., Washington, M. Kay, Grikscheit, Tracy C., Warburton, David, Rosen, Michael J., Frey, Mark R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7864916/
https://www.ncbi.nlm.nih.gov/pubmed/33547321
http://dx.doi.org/10.1038/s41467-021-21113-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7864916/
https://www.ncbi.nlm.nih.gov/pubmed/33547321
http://dx.doi.org/10.1038/s41467-021-21113-7

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