Nonenzymatic polymerase-like template-directed synthesis of acyclic l-threoninol nucleic acid

Evolution of xeno nucleic acid (XNA) world essentially requires template-directed synthesis of XNA polymers. In this study, we demonstrate template-directed synthesis of an acyclic XNA, acyclic l-threoninol nucleic acid (l-aTNA), via chemical ligation mediated by N-cyanoimidazole. The ligation of an...

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Detalles Bibliográficos
Autores principales: Murayama, Keiji, Okita, Hikari, Kuriki, Takumi, Asanuma, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7864931/
https://www.ncbi.nlm.nih.gov/pubmed/33547322
http://dx.doi.org/10.1038/s41467-021-21128-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7864931/
https://www.ncbi.nlm.nih.gov/pubmed/33547322
http://dx.doi.org/10.1038/s41467-021-21128-0

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