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Second-generation lung-on-a-chip with an array of stretchable alveoli made with a biological membrane

The air-blood barrier with its complex architecture and dynamic environment is difficult to mimic in vitro. Lung-on-a-chips enable mimicking the breathing movements using a thin, stretchable PDMS membrane. However, they fail to reproduce the characteristic alveoli network as well as the biochemical...

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Detalles Bibliográficos
Autores principales: Zamprogno, Pauline, Wüthrich, Simon, Achenbach, Sven, Thoma, Giuditta, Stucki, Janick D., Hobi, Nina, Schneider-Daum, Nicole, Lehr, Claus-Michael, Huwer, Hanno, Geiser, Thomas, Schmid, Ralph A., Guenat, Olivier T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7864995/
https://www.ncbi.nlm.nih.gov/pubmed/33547387
http://dx.doi.org/10.1038/s42003-021-01695-0