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Pre-reproductive stress in adolescent female rats alters oocyte microRNA expression and offspring phenotypes: pharmacological interventions and putative mechanisms

Pre-reproductive stress (PRS) to adolescent female rats alters anxiogenic behavior in first (F1)- and second-generation (F2) offspring and increases mRNA expression of corticotropin-releasing factor receptor type 1 (Crhr1) in oocytes and in neonate offspring brain. Here, we ask whether the expressio...

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Detalles Bibliográficos
Autores principales: Zaidan, Hiba, Galiani, Dalia, Gaisler-Salomon, Inna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7865076/
https://www.ncbi.nlm.nih.gov/pubmed/33547270
http://dx.doi.org/10.1038/s41398-021-01220-1