Clinical, molecular, metabolic, and immune features associated with oxidative phosphorylation in melanoma brain metastases

BACKGROUND: Recently, we showed that melanoma brain metastases (MBMs) are characterized by increased utilization of the oxidative phosphorylation (OXPHOS) metabolic pathway compared to melanoma extracranial metastases (ECMs). MBM growth was inhibited by a potent direct OXPHOS inhibitor, but observed...

Descripción completa

Detalles Bibliográficos
Autores principales: Fischer, Grant M, Guerrieri, Renato A, Hu, Qianghua, Joon, Aron Y, Kumar, Swaminathan, Haydu, Lauren E, McQuade, Jennifer L, Vashisht Gopal, Y N, Knighton, Barbara, Deng, Wanleng, Hudgens, Courtney W, Lazar, Alexander J, Tetzlaff, Michael T, Davies, Michael A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Basic and Translational Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7865080/
https://www.ncbi.nlm.nih.gov/pubmed/33575655
http://dx.doi.org/10.1093/noajnl/vdaa177

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7865080/
https://www.ncbi.nlm.nih.gov/pubmed/33575655
http://dx.doi.org/10.1093/noajnl/vdaa177

Ejemplares similares