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Clinical, molecular, metabolic, and immune features associated with oxidative phosphorylation in melanoma brain metastases

BACKGROUND: Recently, we showed that melanoma brain metastases (MBMs) are characterized by increased utilization of the oxidative phosphorylation (OXPHOS) metabolic pathway compared to melanoma extracranial metastases (ECMs). MBM growth was inhibited by a potent direct OXPHOS inhibitor, but observed...

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Detalles Bibliográficos
Autores principales:	Fischer, Grant M, Guerrieri, Renato A, Hu, Qianghua, Joon, Aron Y, Kumar, Swaminathan, Haydu, Lauren E, McQuade, Jennifer L, Vashisht Gopal, Y N, Knighton, Barbara, Deng, Wanleng, Hudgens, Courtney W, Lazar, Alexander J, Tetzlaff, Michael T, Davies, Michael A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Basic and Translational Investigations
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7865080/ https://www.ncbi.nlm.nih.gov/pubmed/33575655 http://dx.doi.org/10.1093/noajnl/vdaa177

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