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5-O-Demethylnobiletin Alleviates CCl(4)-Induced Acute Liver Injury by Equilibrating ROS-Mediated Apoptosis and Autophagy Induction

Polymethoxyflavanoids (PMFs) have exhibited a vast array of therapeutic biological properties. 5-O-Demethylnobiletin (5-DN) is one such PMF having anti-inflammatory activity, yet its role in hepatoprotection has not been studied before. Results from in vitro study revealed that 5-DN did not exert a...

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Detalles Bibliográficos
Autores principales: Chang, Sukkum Ngullie, Kim, Se Ho, Dey, Debasish Kumar, Park, Seon Min, Nasif, Omaima, Bajpai, Vivek K., Kang, Sun Chul, Lee, Jintae, Park, Jae Gyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7865239/
https://www.ncbi.nlm.nih.gov/pubmed/33499185
http://dx.doi.org/10.3390/ijms22031083